PHYTOCHEMICAL SCREENING AND ANTIFUNGAL ACTIVITIES OF Mitracarpus scaber CRUDE EXTRACTS ON SOME PATHOGENIC FUNGI.

PHYTOCHEMICAL SCREENING AND ANTIFUNGAL ACTIVITIES OF Mitracarpus scaber CRUDE EXTRACTS ON SOME PATHOGENIC FUNGI.

Authors

  • Muhammmad
  • I. L. 1Muhammad,
  • R. G.
  • Kassim
  • Z. J.
  • Ndatsu
  • Y.
  • Mohammed
  • U. B.
  • Suleiman
  • A. L.

Keywords:

Antifungal Activities,, Phytochemical, Screening, Isolates, disc and Mitracarpus scaber.

Abstract

Preliminary phytochemicals screening of acetone, aqueous and methanol extracts of Mitracarpus
scaber was carried out using Harbone and Hassan’s method. The phytochemical screening of
acetone extract revealed the presence of anthroquinone, flavonoids, saponin and tannin, while
methanol extract possessed anthroquinone, saponin, steroid, flavonoids and tannins. However,
aqueous extract revealed the presence of tannins and flavonoids, while alkaloid, terpenes, resin,
reducing sugar were absent in all extracts. The antifungal activities of acetone, aqueous and
methanol extracts of Mitracarpus scaber were analysed using discs diffusion method. After 72
hours of incubation, both extracts at 10mg/disc inhibited the growth of Aspergillus fumigatus,
Aspergillus flavus, Aspergillus niger, Mucor mucedo, Microsporium canis, Fusarium solani,
Candida albican, Epidermophyton floccosum and Trichopyton verrucosum. The methanol extract
of Mitracarpu sscaber was more active than acetone and aqueous extracts. The activities of the
extracts may be responsible for their utilization in the traditional treatment of various ailments
associated with the test organisms.

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Published

2023-08-08

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Section

Articles